Before AI went mainstream, Andrew Mayne was an outsider—an author and magician exploring the edges of human creativity. That same curiosity led him inside OpenAI, where he became the company’s first prompt engineer and helped shape the way humans and machines think together.
In this talk, he shares lessons from inside one of the world’s most influential AI labs
A decade ago, Andrew Mayne bet his career on artificial intelligence—and watched it evolve from a lab curiosity into the defining force of our time. From the inside of OpenAI to the frontlines of startup innovation, he has seen how quickly the future arrives and who actually captures its value.
In this talk, Mayne offers a grounded look at where AI is going next—what’s real, what’s noise, and what leaders need to prepare for now. It’s an insider’s guide to navigating the next wave of intelligence, from models to markets to mindsets.
From OpenAI to Interdimensional, Andrew Mayne has seen firsthand what separates companies that talk about AI from those that win with it. This session reveals how to build and lead teams that amplify human capability with intelligent tools—where small, focused groups can out-innovate entire industries.
He breaks down the playbook for assembling AI-literate teams, integrating models into real workflows, and fostering a culture where experimentation drives measurable growth.
Andrew Mayne is a technology entrepreneur, AI pioneer, bestselling author, and one of the most influential voices helping organizations understand and apply artificial intelligence. As OpenAI’s first Prompt Engineer and former Science Communicator, Andrew played a pivotal role in the early development, adoption, and public understanding of transformative AI technologies including GPT-3, ChatGPT, and GPT-4.
Working directly alongside OpenAI researchers and engineers, Andrew helped bridge the gap between cutting-edge AI research and real-world applications, translating complex concepts into practical insights for businesses, creators, and technology leaders. Today, he continues to shape conversations around AI as host of The OpenAI Podcast, where he interviews the innovators building the future of artificial intelligence.
As founder of Interdimensional, Andrew advises organizations on AI adoption, innovation, productivity, and emerging technology strategy. His unique ability to make sophisticated technologies accessible has made him a highly sought-after keynote speaker for executives, leadership teams, and organizations navigating rapid technological change.
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Helps organizations turn disruption into opportunity through future-focused strategy.
He helps leaders anticipate change and build strategies for future success.
He helps organizations prepare for change and future disruption.
He helps organizations turn disruption into opportunity and growth.
He helps teams turn trends into actionable growth strategies.
He helps leaders rethink technology’s impact on society and humanity.
He pioneers AI breakthroughs that accelerate science and global innovation.
She helps organizations innovate boldly and rethink what’s possible for growth.
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