Andrew Mayne: OpenAI’s Science Communicator

    AI expert, futurist, and former OpenAI Prompt Engineer Andrew Mayne helps organizations understand artificial intelligence, unlock innovation, and prepare for technological transformation.

    Andrew Mayne - Image 01 (June 4, 2026)

    Quick Facts:

      • OpenAI’s first Prompt Engineer
      • Former Science Communicator at OpenAI
      • Contributed to the development and adoption of GPT-3, ChatGPT, and GPT-4
      • Host of The OpenAI Podcast
    • Formats:
    • Keynote Speaker | AI Expert | Futurist |
    • Audiences:
    • Business leaders, executives, entrepreneurs, technology teams, innovators, policymakers, and organizations preparing for AI-driven transformation.
    • Outcomes:
      1. Understand the practical implications of artificial intelligence for business
      2. Learn how AI can drive innovation, productivity, and competitive advantage
      3. Gain insight into future technology trends and organizational readiness
    Reading time: 3 min
    Reviews: (0 reviews)
    • Travels from: San Francisco, CA
    • **US Fee range: $75,001 - $100,000

    Talent Services

    Keynote Topics:

    Before AI went mainstream, Andrew Mayne was an outsider—an author and magician exploring the edges of human creativity. That same curiosity led him inside OpenAI, where he became the company’s first prompt engineer and helped shape the way humans and machines think together.

    In this talk, he shares lessons from inside one of the world’s most influential AI labs

    • how to recognize inflection points before they happen, turn uncertainty into momentum, and build a career that thrives through technological upheaval. It’s a roadmap for anyone, from executives to creators, who wants to navigate the AI revolution not as a passenger, but as a pilot.

    A decade ago, Andrew Mayne bet his career on artificial intelligence—and watched it evolve from a lab curiosity into the defining force of our time. From the inside of OpenAI to the frontlines of startup innovation, he has seen how quickly the future arrives and who actually captures its value.

    In this talk, Mayne offers a grounded look at where AI is going next—what’s real, what’s noise, and what leaders need to prepare for now. It’s an insider’s guide to navigating the next wave of intelligence, from models to markets to mindsets.

    From OpenAI to Interdimensional, Andrew Mayne has seen firsthand what separates companies that talk about AI from those that win with it. This session reveals how to build and lead teams that amplify human capability with intelligent tools—where small, focused groups can out-innovate entire industries.

    He breaks down the playbook for assembling AI-literate teams, integrating models into real workflows, and fostering a culture where experimentation drives measurable growth.

    Talent Short Bio

    Andrew Mayne is a technology entrepreneur, AI pioneer, bestselling author, and one of the most influential voices helping organizations understand and apply artificial intelligence. As OpenAI’s first Prompt Engineer and former Science Communicator, Andrew played a pivotal role in the early development, adoption, and public understanding of transformative AI technologies including GPT-3, ChatGPT, and GPT-4.

    Working directly alongside OpenAI researchers and engineers, Andrew helped bridge the gap between cutting-edge AI research and real-world applications, translating complex concepts into practical insights for businesses, creators, and technology leaders. Today, he continues to shape conversations around AI as host of The OpenAI Podcast, where he interviews the innovators building the future of artificial intelligence.

    As founder of Interdimensional, Andrew advises organizations on AI adoption, innovation, productivity, and emerging technology strategy. His unique ability to make sophisticated technologies accessible has made him a highly sought-after keynote speaker for executives, leadership teams, and organizations navigating rapid technological change.

    Andrew Mayne is a technology entrepreneur, AI pioneer, bestselling author, and one of the most recognized voices translating artificial intelligence for business audiences today. As OpenAI’s first Prompt Engineer and former Science Communicator, Andrew played a pivotal role in helping shape the early development and adoption of groundbreaking AI technologies, including GPT-3, ChatGPT, and GPT-4.

    During his time at OpenAI, Andrew worked alongside researchers and engineers to explore how advanced AI systems could be effectively understood, communicated, and applied in the real world. Today, he continues to bridge the gap between cutting-edge technology and practical business application as host of The OpenAI Podcast, where he conducts in-depth conversations with the people building and shaping the future of artificial intelligence from inside OpenAI.

    Andrew Mayne is also the founder of Interdimensional, an AI consultancy that helps organizations understand, adopt, and leverage artificial intelligence to drive innovation, productivity, and competitive advantage. His ability to make complex technologies accessible has made him a sought-after keynote speaker for business leaders, technology professionals, and organizations navigating rapid technological change.

    What sets Andrew apart is his unique blend of scientific curiosity, creativity, and real-world experimentation. Long before becoming a leading voice in AI, he built an international reputation as an inventor, illusionist, television personality, and bestselling author. His unconventional career has been driven by a lifelong fascination with how people perceive, understand, and interact with the world around them—an interest that now informs his work in artificial intelligence and human-machine collaboration.

    A Wall Street Journal bestselling novelist, Andrew has written numerous acclaimed thrillers and science-based fiction titles. His novels have received industry recognition, including nominations for the Edgar Award and the Thriller Award. His bestselling novel The Naturalist became an Amazon Charts bestseller and held the number one position across all books on Amazon for six consecutive weeks. Before securing his first major publishing deal, Andrew was recognized by Amazon as one of the platform’s top independent authors.

    Beyond technology and writing, Andrew Mayne has built a reputation for pushing the boundaries of innovation and exploration. He starred in the Discovery Channel special Andrew Mayne: Ghost Diver, where he developed and tested groundbreaking underwater camouflage technology while researching great white shark behavior. His work exploring perception, engineering, and behavioral science led to the development of artificial intelligence models inspired by shark behavior, which were later used to create virtual reality training simulations.

    Andrew’s passion for learning and education has also driven significant philanthropic initiatives. Supported by the Johnny Carson Foundation and the James Randi Educational Foundation, he created programs that use magic as a tool for teaching critical thinking and scientific reasoning in schools. His educational segments introducing children to science through magic aired nationally on public television.

    As a creative consultant, Andrew Mayne has worked behind the scenes with some of the world’s most celebrated performers, including David Copperfield, Penn & Teller, and David Blaine. His inventions and creative concepts have been performed globally and have even contributed to experiments conducted aboard the International Space Station.

    Today, Andrew Mayne brings a rare perspective to audiences worldwide—combining firsthand experience at the forefront of artificial intelligence with the creativity of a storyteller, the curiosity of an inventor, and the insight of a futurist. His presentations help organizations understand what AI means today, what comes next, and how to harness emerging technologies to create meaningful opportunities in a rapidly changing world.

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